منابع مشابه
Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate
This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.
متن کامل2-Ethyl-5-nitroaniline
The mol-ecule of the title compound, C(8)H(10)N(2)O(2), is nearly planar [maximum deviation of 0.163 (3) Å for one of the O atoms of the NO(2) group]. In the crystal structure, weak inter-molecular N-H⋯N and C-H⋯O hydrogen bonds link the mol-ecules into chains, forming R(2) (2)(10) ring motifs.
متن کاملEthyl 2-(2-hydroxy-5-nitrophenyl)acetate
In the crystal structure of the title compound, C(10)H(11)NO(5), inter-molecular O-H⋯O hydrogen bonds link the mol-ecules into chains along the b-axis direction. Weak C-H.·O hydrogen bonds also occur.
متن کاملEvaluation of (5R,6R)-5-Bromo-6-Ethoxy-5-Ethyl-5,6-Dihydro-2\'- Deoxyuridine as a Brain-Targeted Prodrug of 5-Ethyl-2\'- Deoxyuridine
(+)-Trans-(5R,6R)-5-bromo-6-ethoxy-5-ethyl-5,6-dihydro-2'-deoxyuridine [(5R,6R)-BEEDU], a potential brain-targeted prodrug of 5-ethyl-2'-deoxyuridine (EDU), was synthesized by the regiospecific addition of BrOEt to the 5,6-olefinic bond of EDU. (5R,6R)-BEEDU is more lipophilic (log P = 0.04) than EDU (log P = -1.09). In vitro incubation of (5R,6R)-BEEDU with rat whole blood and brain homogena...
متن کامل[5-Chloro-2-hydroxy-N′-(2-oxidobenzylidene)benzohydrazidato]pyridinecopper(II)
In the title complex, [Cu(C(14)H(9)ClN(2)O(3))(C(5)H(5)N)], the Cu(II) ion exhibits a distorted trans-CuN(2)O(2) square-planar geometry arising from the O,O,N-tridentate ligand and a pyridine mol-ecule. An intra-molecular O-H⋯N hydrogen bond occurs. In the crystal structure, weak inter-molecular C-H⋯π inter-actions generate a chain. The crystal studied was an inversion twin.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2011
ISSN: 1600-5368
DOI: 10.1107/s1600536811000389